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Innovative safe chlorine products for wounds, skin antisepsis and medical device disinfection

Even though chlorine is not the only active chemical in our product line, chlorine is truly the core of our products. Today chlorine is the number one disinfectant worldwide. The effectiveness of this ingredient is demonstrated by large numbers of scientific reports and there is still no known strain of bacteria resistant to it. Sodium hypochlorite's potential has not been fully exploited in the medical field due to the unavailability of a pharmaceutical grade product: manufacturers are interested in sodium hypochlorite for industrial use ( big quantity, low quality, no quality control ).

Alcavis International represents the exception: our chemists have committed themselves to discovering a method of producting a pharmaceutical grade hypochlorite solution that is effective at killing bacteria, fast acting, non-destructive to PVC materials (found in catheters), stable for long periods of time, easy to use, and the safe for patient and staff.

Alcavis products are chlorine based disinfectants electrolytically produced by using a brine of purified water and sodium chloride (salt). The main features of our products are: low concentrations of available chlorine (1.1%), high concentration of sodium chloride (18%) and, overall, excellent stability. We do not add sodium hydroxide to stabilize our products like that of common "bleach". This gives us relevant advantages over bleach from a microbiological and clinical point of view.


At the origins of chlorine
Chlorine was discovered in 1774 by Carl Wilhelm Scheele, but only in 1810 Humphry Davy confirmed that it was an element and suggested naming it after the Greek word "chloros", meaning pale green.
In the late 19th century famous scientists such as Sommelweiss and Koch realize the high disinfectant potential of chlorine gas.
The way chlorine acts
All the chlorine-based disinfectants act by releasing hypochlorous acid. Being similar in molecular size and structure to water, hypochlorous acid can easily cross the microbial cell membrane. Its intracellular target is represented by some enzymes of the microbial energy metabolism. The result is that the action of chlorine on bacteria is powerful, lethal and has no possibility of microbial resistance.
The pH factor in chlorine-based disinfectants
pH affects activity
When pH decreases hypochlorous acid concentration increases, and ORP (oxidation reduction potential) increases. The lower the pH, the higher the activity and the tolerability.
pH affects stability
When pH decreases then stability decreases dramatically. This is the reason why industrial sodium hypochlorite has strong alkalinization, which adds stability (not enough for a pharmaceutical product) but reduces tolerability and effectiveness.

 


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